Hey Andrew,
Try navigating to your main music folder and look for the folder named _Serato_, when the program is closed open the recordings folder and move all your previous recordings somewhere else, ie, desktop.
Will the program open now?
If not can you please reply to me with your computers full specs and a list of all USB devices connected. Also can you follow these steps to get me your crash report:
serato.com ?
Cheers, Sam